Anti-Trem2 antibody treatment as Alzheimer therapy
Modulating Trem2 signaling through Trem2 antagonistic antibodies can alter microglia function and cause disease-relevant changes in Alzheimer’s disease.
Asymmetry of Fibrillar Plaque Burden in Amyloid Mouse Models
Investigating the symmetry of fibrillar plaques on AD mouse models confirms an asymmetric pattern, similar to Alzheimer’s disease patients, which translated into regional microglia activation.
TSHR-specific lymphocytes in Graves´ disease patient blood
Novel major histocompatibility complex class II (MHC II) tetramers identified specific T lymphocytes for thyroid stimulating hormone receptors (TSHR) in hyperthyroid mice and in human blood cells [...]
