Dysregulation of the immune system
Our immune system has to distinguish exactly what belongs to our body and what is foreign to it. Sometimes this distinction does not function and the immune system reacts either too strongly or too weakly. This contributes to many (auto)immune diseases, including diseases in which the body attacks itself.
ISAR Bioscience’s research aims to restore a healthy balance of the immune system. To this end, immune cells derived from induced pluripotent stem cells (iPS) are being generated to test them for the treatment of (auto)immune diseases.
Novel peptides (protein fragments) have also been designed; they are intended to advance the therapy of autoimmune diseases. The peptides are supposed to create a healthy tolerance to a harmless antigen and thus prevent excessive reactions of the immune system.