Sci­en­tis­t/­Post-doc – Immu­no­logy (gn)

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Sci­en­tis­t/­Post-doc – Immu­no­logy (gn)

ISAR Bioscience GmbH is a trans­la­tio­nal rese­arch com­pany in Plan­egg near Munich, sup­ported by the Free State of Bavaria.

Our rese­arch focu­ses on (auto-)immune dise­a­ses, dege­ne­ra­tive dise­a­ses of the brain (Alzheimer’s) and heart dise­a­ses (infarc­tion, car­diac fail­ure). We use human indu­ced plu­ri­po­tent stem cell (iPSC) tech­no­lo­gies to deve­lop dise­ase models for the dis­co­very of novel drugs and cell the­ra­pies. In doing so, we enter into stra­te­gic part­ner­ships with rese­arch insti­tu­ti­ons and indus­trial companies.

We are loo­king for Sci­en­tist­s/­Post-doc to join our team (full-time posi­tion). Sui­ta­ble can­di­da­tes will join a vibrant and gro­wing Start-up com­pany, which is deve­lo­ping the next gene­ra­tion of dise­ase models by dif­fe­ren­tia­ting human indu­ced plu­ri­po­tent stem cells (hiPSC) into rele­vant cells of interest.

Respon­si­bi­li­ties

  • Con­tri­bu­tion to rese­arch and deve­lo­p­ment of novel the­ra­pies for (auto-)immune dise­a­ses (inclu­ding (long-term)culture of macro­pha­ges, T and B lym­pho­cytes, NK cells, den­dri­tic cells)
  • Estab­lish and main­tain cell lines, par­ti­ally under qua­lity-con­trol­led conditions
  • Iso­late peri­phe­ral blood mono­cytes (PBMCs), pre­pa­ra­tion of lymphocytes
  • T- and B lym­pho­cyte assays, inclu­ding pep­tide sti­mu­la­tion, cyto­kine release and FACS
  • Estab­lish and deve­lop cell based assays and dif­fe­ren­tia­tion protocols
  • Dif­fe­ren­tiate human indu­ced plu­ri­po­tent cells (hiPSC) for rese­arch pur­po­ses, and to gene­rate mas­ter cell banks under GMP conditions
  • Mani­pu­late human immune cells by various nucleic acid deli­very techniques
  • Cri­ti­cally ana­lyze and inter­pret data and define rea­li­stic time­lines for studies
  • Work clo­sely with and com­mu­ni­cate results to inter­nal teams as well as to exter­nal partners

Qua­li­fi­ca­ti­ons

  • Ph.D. in Immu­no­logy, Mole­cu­lar Bio­logy or rela­ted field
  • Pro­found exper­tise in immu­no­lo­gi­cal methods, such as FACS, ELISA etc. as well as in mamma­lian cell cul­ture tech­ni­ques and cell mani­pu­la­tion (transduction/ trans­fec­tion) is essential
  • Sound know­ledge and track-record with focus on human T and NK cell bio­logy is a plus
  • Good com­mand of Eng­lish (both writ­ten and spo­ken); Know­ledge of Ger­man is an advantage

Our offer

We offer the spe­cial oppor­tu­nity to help shape the deve­lo­p­ment of a new rese­arch com­pany in an inter­di­sci­pli­nary team with pio­nee­ring spi­rit. You will be given exci­ting tasks and per­so­nal deve­lo­p­ment. The salary will depend on qua­li­fi­ca­ti­ons and pro­fes­sio­nal expe­ri­ence and is cal­cu­la­ted in accordance with the civil ser­vice salary sca­les. The posi­tion is initi­ally tem­po­rary, but there is the pos­si­bi­lity of an extension.
Please send your cover let­ter and com­plete appli­ca­tion docu­ments with CV, references/ recom­men­da­tion let­ter to recruitment@isarbioscience.de. Please indi­cate „Sci­en­tis­t/­Post-doc Immu­no­logy“ in the sub­ject line. If you have any ques­ti­ons, please cont­act Dr. Chris­tiane Schie­gerl, Tel: 089-356475-413.

Cont­act

Please send your cover let­ter and com­plete appli­ca­tion docu­ments with CV, references/ recom­men­da­tion let­ter to recruitment@isarbioscience.de Please indi­cate „Sci­en­tis­t/­Post-doc Immu­no­logy“ in the sub­ject line. If you have any ques­ti­ons, please cont­act Dr. Chris­tiane Schie­gerl, Tel: 089-356475-413.

  • Dr. Chris­tiane Schiegerl
    Dr. Chris­tiane Schiegerl

    Für Rückfragen stehe ich Ihnen gerne zur Verfügung.

    089-356475-413

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