Sci­en­tist – Genome Engi­nee­ring (gn)

ISAR Bioscience GmbH is a trans­la­tio­nal rese­arch com­pany in Plan­egg near Munich, sup­ported by the Free State of Bavaria.

Our rese­arch focu­ses on (auto-)immune dise­a­ses, dege­ne­ra­tive dise­a­ses of the brain (Alzheimer’s) and heart dise­a­ses (infarc­tion, car­diac fail­ure). We use human indu­ced plu­ri­po­tent stem cell (iPSC) tech­no­lo­gies to deve­lop dise­ase models for the dis­co­very of novel drugs and cell the­ra­pies. In doing so, we enter into stra­te­gic part­ner­ships with rese­arch insti­tu­ti­ons and indus­trial companies.

Sci­en­tist – Genome Engi­nee­ring (gn)

We are loo­king for a sci­en­tist to join our team (full-time posi­tion). Sui­ta­ble can­di­da­tes will join a vibrant and gro­wing start-up com­pany that deve­lops the next gene­ra­tion of dise­ase models and cell the­ra­pies by editing and dif­fe­ren­tia­ting human indu­ced plu­ri­po­tent stem cells (hiPSC) into rele­vant cells of interest.

Pri­mary responsibilities

  • Lead and con­tri­bute to genome engi­nee­ring pro­jects, uti­li­zing advan­ced gene-editing tech­no­lo­gies (e.g., CRISPR/Cas9, base editing, prime editing)
  • Ana­lyze and inter­pret geno­mic data, employ­ing mole­cu­lar and cell bio­logy techniques
  • Design, exe­cute, and opti­mize expe­ri­ments in stem cell bio­logy, inclu­ding iPSC cul­ture, dif­fe­ren­tia­tion, and characterization
  • Con­tri­bute to the gene­ra­tion of mas­ter cell banks under GMP conditions
  • Mani­pu­late human cells by various nucleic acid deli­very techniques
  • Cri­ti­cally ana­lyze and inter­pret data and define rea­li­stic time­lines for studies
  • Work clo­sely with and com­mu­ni­cate results to inter­nal teams as well as to exter­nal partners

Qua­li­fi­ca­ti­ons

  • Ph.D. in Mole­cu­lar Bio­logy, Gene­tics, Stem Cell Bio­logy, or a rela­ted field
  • Pro­ven exper­tise in genome engi­nee­ring pro­jects, inclu­ding CRISPR-based gene editing
  • Pre­fer­a­bly a back­ground in stem cell bio­logy, inclu­ding hands-on expe­ri­ence with iPSC cul­ture and differentiation
  • Good com­mand of Eng­lish as well as German

Our offer

We offer the spe­cial oppor­tu­nity to help shape the deve­lo­p­ment of a new rese­arch com­pany in an inter­di­sci­pli­nary team with pio­nee­ring spi­rit. You will be invol­ved in exci­ting tasks and per­so­nal deve­lo­p­ment. The salary will depend on qua­li­fi­ca­ti­ons and pro­fes­sio­nal expe­ri­ence and is cal­cu­la­ted in accordance with the civil ser­vice salary sca­les (TVL). The posi­tion is initi­ally for two years with the pos­si­bi­lity of a per­ma­nent extension.

Cont­act

Please send your cover let­ter and com­plete appli­ca­tion docu­ments with CV, references/ recom­men­da­tion let­ter to recruitment@isarbioscience.de . Please indi­cate the title of the job adver­ti­se­ment in the sub­ject line. Alter­na­tively you can use the Appli­ca­tion Form below.

  • Dr. Chris­tiane Schiegerl
    Dr. Chris­tiane Schiegerl

    Für Rückfragen stehe ich Ihnen gerne zur Verfügung.

    089-356475-413

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