Sci­en­tist – Bio­che­mis­try (gn)

By p564569

Sci­en­tist – Bio­che­mis­try (gn)

ISAR Bioscience GmbH is a trans­la­tio­nal rese­arch com­pany in Plan­egg near Munich, sup­ported by the Free State of Bavaria. 

Our rese­arch focu­ses on (auto-)immune dise­a­ses, dege­ne­ra­tive dise­a­ses of the brain (Alzheimer’s) and the heart. We use human indu­ced plu­ri­po­tent stem cell (iPSC) tech­no­lo­gies to deve­lop dise­ase models for the dis­co­very of novel drugs and cell the­ra­pies. In doing so, we enter into stra­te­gic part­ner­ships with rese­arch insti­tu­ti­ons and indus­trial companies.

We are loo­king for a sci­en­tist to join our team (full-time posi­tion). Sui­ta­ble can­di­da­tes will join a vibrant and gro­wing start-up com­pany that deve­lops the next gene­ra­tion of dise­ase models and cell the­ra­pies by editing and dif­fe­ren­tia­ting human indu­ced plu­ri­po­tent stem cells (hiPSC) into rele­vant cells of interest.

Respon­si­bi­li­ties

  • Con­tri­bu­tion to rese­arch and deve­lo­p­ment of novel the­ra­pies for neuro-dege­ne­ra­tive diseases
  • Estab­lish and main­tain cell lines for pro­duc­tion of pro­te­ins under qua­lity-con­trol­led con­di­ti­ons, e. g. CHO and HEK-293 cells
  • Opti­mize expres­sion levels of tran­si­ently trans­fec­ted and sta­ble cell lines
  • Design, opti­mise, purify and cha­rac­te­rize the­ra­peu­tic antibodies
  • Estab­lish and per­form ana­ly­ti­cal stu­dies and method vali­da­ti­ons (using ELISA, FACS and rela­ted methods)
  • Con­tri­bute to the gene­ra­tion of mas­ter cell banks under GMP conditions
  • Cri­ti­cally ana­lyze and inter­pret data and define rea­li­stic time­lines for studies
  • Work clo­sely with and com­mu­ni­cate results to inter­nal teams as well as to exter­nal partners

Qua­li­fi­ca­ti­ons

  • Ph.D. in Bio­che­mis­try, Pro­tein Engi­nee­ring , Immu­no­logy or rela­ted field
  • Mamma­lian cell cul­ture, trans­fec­tions and pro­tein puri­fi­ca­tion and cha­rac­te­riza­tion is essential
  • Tho­rough under­stan­ding or expe­ri­ence in instru­men­tal ana­ly­tics, pro­tein bio­phy­sics or qua­lity manage­ment stan­dards would be a plus
  • Struc­tu­red and inde­pen­dent way of working as well as ana­ly­ti­cal skills
  • Good com­mand of Eng­lish as well as German

Our offer

We offer the spe­cial oppor­tu­nity to help shape the deve­lo­p­ment of a new rese­arch com­pany in an inter­di­sci­pli­nary team with pio­nee­ring spi­rit. You will be invol­ved in exci­ting tasks and per­so­nal deve­lo­p­ment. The salary will depend on qua­li­fi­ca­ti­ons and pro­fes­sio­nal expe­ri­ence and is cal­cu­la­ted in accordance with the civil ser­vice salary sca­les (TVL). We also offer sup­port with com­pany pen­sion sche­mes, a wide range of sports acti­vi­ties and Job­Rad lea­sing. The posi­tion is initi­ally for two years with the pos­si­bi­lity of a per­ma­nent extension.

Kon­takt

Bitte schi­cken Sie Ihre Bewer­bungs­un­ter­la­gen mit Lebens­lauf, Arbeits­zeug­nis­sen bzw. Emp­feh­lungs­schrei­ben an recruitment@isarbioscience.de und ver­wen­den Sie in der Betreff­zeile den Titel der Stel­len­aus­schrei­bung. Alter­na­tiv kön­nen Sie sich über unten ste­hen­des Bewer­bungs­for­mu­lar bewerben.

  • Dr. Chris­tiane Schiegerl
    Dr. Chris­tiane Schiegerl

    Für Rückfragen stehe ich Ihnen gerne zur Verfügung.

    089-356475-413

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