Sci­ent­ist/­Post-doc – Immun­o­logy (gn)

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Sci­ent­ist/­Post-doc – Immun­o­logy (gn)

ISAR Bioscience GmbH is a trans­la­tional research com­pany in Planegg near Munich, sup­por­ted by the Free State of Bavaria.

Our research focuses on (auto-)immune dis­eases, degen­er­at­ive dis­eases of the brain (Alzheimer’s) and heart dis­eases (infarc­tion, car­diac fail­ure). We use human induced pluri­po­tent stem cell (iPSC) tech­no­lo­gies to develop dis­ease mod­els for the dis­cov­ery of novel drugs and cell ther­apies. In doing so, we enter into stra­tegic part­ner­ships with research insti­tu­tions and indus­trial companies.

We are look­ing for Sci­ent­ist­s/­Post-doc to join our team (full-time pos­i­tion). Suit­able can­did­ates will join a vibrant and grow­ing Start-up com­pany, which is devel­op­ing the next gen­er­a­tion of dis­ease mod­els by dif­fer­en­ti­at­ing human induced pluri­po­tent stem cells (hiPSC) into rel­ev­ant cells of interest.

Respons­ib­il­it­ies

  • Con­tri­bu­tion to research and devel­op­ment of novel ther­apies for (auto-)immune dis­eases (includ­ing (long-term)culture of mac­ro­phages, T and B lymph­o­cytes, NK cells, dend­ritic cells)
  • Estab­lish and main­tain cell lines, par­tially under qual­ity-con­trolled conditions
  • Isol­ate peri­pheral blood mono­cytes (PBMCs), pre­par­a­tion of lymphocytes
  • T- and B lymph­o­cyte assays, includ­ing pep­tide stim­u­la­tion, cytokine release and FACS
  • Estab­lish and develop cell based assays and dif­fer­en­ti­ation protocols
  • Dif­fer­en­ti­ate human induced pluri­po­tent cells (hiPSC) for research pur­poses, and to gen­er­ate mas­ter cell banks under GMP conditions
  • Manip­u­late human immune cells by vari­ous nuc­leic acid deliv­ery techniques
  • Crit­ic­ally ana­lyze and inter­pret data and define real­istic timelines for studies
  • Work closely with and com­mu­nic­ate res­ults to internal teams as well as to external partners

Qual­i­fic­a­tions

  • Ph.D. in Immun­o­logy, Molecu­lar Bio­logy or related field
  • Pro­found expert­ise in immun­o­lo­gical meth­ods, such as FACS, ELISA etc. as well as in mam­malian cell cul­ture tech­niques and cell manip­u­la­tion (transduction/ trans­fec­tion) is essential
  • Sound know­ledge and track-record with focus on human T and NK cell bio­logy is a plus
  • Good com­mand of Eng­lish (both writ­ten and spoken); Know­ledge of Ger­man is an advantage

Our offer

We offer the spe­cial oppor­tun­ity to help shape the devel­op­ment of a new research com­pany in an inter­dis­cip­lin­ary team with pion­eer­ing spirit. You will be given excit­ing tasks and per­sonal devel­op­ment. The salary will depend on qual­i­fic­a­tions and pro­fes­sional exper­i­ence and is cal­cu­lated in accord­ance with the civil ser­vice salary scales. The pos­i­tion is ini­tially tem­por­ary, but there is the pos­sib­il­ity of an extension.

Con­tact

Please send your cover let­ter and com­plete applic­a­tion doc­u­ments with CV, references/ recom­mend­a­tion let­ter to recruitment@isarbioscience.de Please indic­ate “Sci­ent­ist/­Post-doc Immun­o­logy” in the sub­ject line. If you have any ques­tions, please con­tact Dr. Chris­ti­ane Schiegerl, Tel: 089-356475-413.

  • Dr. Chris­ti­ane Schiegerl
    Dr. Chris­ti­ane Schiegerl

    Please do not hes­it­ate to con­tact me if you have any questions.

    089-356475-413

Apply now

Please send us your applic­a­tion doc­u­ments with CV, ref­er­ences or let­ters of recom­mend­a­tion as a PDF file.

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