Sci­ent­ist – Gen­ome Engin­eer­ing (gn)

ISAR Bioscience GmbH is a trans­la­tional research com­pany in Planegg near Munich, sup­por­ted by the Free State of Bavaria.

Our research focuses on (auto-)immune dis­eases, degen­er­at­ive dis­eases of the brain (Alzheimer’s) and heart dis­eases (infarc­tion, car­diac fail­ure). We use human induced pluri­po­tent stem cell (iPSC) tech­no­lo­gies to develop dis­ease mod­els for the dis­cov­ery of novel drugs and cell ther­apies. In doing so, we enter into stra­tegic part­ner­ships with research insti­tu­tions and indus­trial companies

Sci­ent­ist – Gen­ome Engin­eer­ing (gn)

We are look­ing for a sci­ent­ist to join our team (full-time pos­i­tion). Suit­able can­did­ates will join a vibrant and grow­ing start-up com­pany that devel­ops the next gen­er­a­tion of dis­ease mod­els and cell ther­apies by edit­ing and dif­fer­en­ti­at­ing human induced pluri­po­tent stem cells (hiPSC) into rel­ev­ant cells of interest.

Respons­ib­il­it­ies

  • Lead and con­trib­ute to gen­ome engin­eer­ing pro­jects, util­iz­ing advanced gene-edit­ing tech­no­lo­gies (e.g., CRISPR/Cas9, base edit­ing, prime editing)
  • Ana­lyze and inter­pret gen­omic data, employ­ing molecu­lar and cell bio­logy techniques
  • Design, execute, and optim­ize exper­i­ments in stem cell bio­logy, includ­ing iPSC cul­ture, dif­fer­en­ti­ation, and characterization
  • Con­trib­ute to the gen­er­a­tion of mas­ter cell banks under GMP conditions
  • Manip­u­late human cells by vari­ous nuc­leic acid deliv­ery techniques
  • Crit­ic­ally ana­lyze and inter­pret data and define real­istic timelines for studies
  • Work closely with and com­mu­nic­ate res­ults to internal teams as well as to external partners

Qual­i­fic­a­tions

  • Ph.D. in Molecu­lar Bio­logy, Genet­ics, Stem Cell Bio­logy, or a related field
  • Proven expert­ise in gen­ome engin­eer­ing pro­jects, includ­ing CRISPR-based gene editing
  • Prefer­ably a back­ground in stem cell bio­logy, includ­ing hands-on exper­i­ence with iPSC cul­ture and differentiation
  • Good com­mand of Eng­lish as well as German

Our offer

We offer the spe­cial oppor­tun­ity to help shape the devel­op­ment of a new research com­pany in an inter­dis­cip­lin­ary team with pion­eer­ing spirit. You will be involved in excit­ing tasks and per­sonal devel­op­ment. The salary will depend on qual­i­fic­a­tions and pro­fes­sional exper­i­ence and is cal­cu­lated in accord­ance with the civil ser­vice salary scales (TVL). The pos­i­tion is ini­tially for two years with the pos­sib­il­ity of a per­man­ent extension.

Con­tact

Please send your cover let­ter and com­plete applic­a­tion doc­u­ments with CV, references/ recom­mend­a­tion let­ter to recruitment@isarbioscience.de . Please indic­ate the title of the job advert­ise­ment in the sub­ject line. Altern­at­ively you can use the Applic­a­tion Form below.

  • Dr. Chris­ti­ane Schiegerl
    Dr. Chris­ti­ane Schiegerl

    Please do not hes­it­ate to con­tact me if you have any questions.

    089-356475-413

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Please send us your applic­a­tion doc­u­ments with CV, ref­er­ences or let­ters of recom­mend­a­tion as a PDF file.

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