Sci­ent­ist – Blood Brain Bar­rier (gn)


ISAR Bioscience GmbH is a trans­la­tional research com­pany in Planegg near Munich, sup­por­ted by the Free State of Bavaria.

Our research focuses on degen­er­at­ive dis­eases of the brain (Alzheimer’s), the heart (infarc­tion, car­diac insuf­fi­ciency) and the immune sys­tem. We use induced pluri­po­tent stem cell tech­no­lo­gies (iPSC) to develop dis­ease mod­els for the dis­cov­ery of novel drugs. In doing so, we enter into stra­tegic part­ner­ships with research insti­tu­tions and indus­trial companies.

To expand our “Neuro­de­gen­er­a­tion Pro­gram” team, we are filling the pos­i­tion full-time as of 01.04.2023

Sci­ent­ist – Blood Brain Bar­rier (gn)

Primary respons­ib­il­it­ies

  • Develop a robust and repro­du­cible sys­tem to model the Blood Brain Bar­rier (BBB) using stable cell lines or/and hiPSC-derived cells
  • Estab­lish robust and scal­able assays to mon­itor deliv­ery of bio­lo­gics, such as anti­bod­ies for brain disorder
  • Develop and optim­ize BBB tar­get­ing antibodies
  • Crit­ic­ally ana­lyze and inter­pret data and define real­istic timelines for studies
  • Work closely with and com­mu­nic­ate res­ults to internal teams as well as to external partners


  • PhD in Neur­os­cience, Vas­cu­lar Bio­logy, (Neuro)immunology or a related discipline
  • Industry exper­i­ence is a plus
  • Back­ground in BBB research or vas­cu­lar biology
  • Exper­i­ence in pro­tein engin­eer­ing, pro­tein design and pro­tein pro­duc­tion (prefer­able)
  • Anti­body engin­eer­ing back­ground (valu­able)
  • Know­ledge of the drug discovery/development space would be an asset
  • Exper­i­ence with transwell or micro­fluidic device and high-res­ol­u­tion micro­scopy like con­focal is a plus
  • Good com­mand of Eng­lish (both writ­ten and spoken); Know­ledge of Ger­man is an advantage

Our offer

We offer the spe­cial oppor­tun­ity to help shape the devel­op­ment of a new research com­pany in an inter­dis­cip­lin­ary team with pion­eer­ing spirit. You will be given excit­ing tasks and per­sonal devel­op­ment. The salary will depend on qual­i­fic­a­tions and pro­fes­sional exper­i­ence and is cal­cu­lated in accord­ance with the civil ser­vice salary scales. The pos­i­tion is ini­tially temporary.


Please send your cover let­ter and com­plete applic­a­tion doc­u­ments with CV, references/ recom­mend­a­tion let­ter to . Please indic­ate the title of the job advert­ise­ment in the sub­ject line. Altern­at­ively you can use the Applic­a­tion Form below.

  • Dr. Chris­ti­ane Schiegerl
    Dr. Chris­ti­ane Schiegerl

    Please do not hes­it­ate to con­tact me if you have any questions.


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Please send us your applic­a­tion doc­u­ments with CV, ref­er­ences or let­ters of recom­mend­a­tion as a PDF file.

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