Sci­ent­ist – Bio­chem­istry (gn)

By p564569

Sci­ent­ist – Bio­chem­istry (gn)

ISAR Bioscience GmbH is a trans­la­tional research com­pany in Planegg near Munich, sup­por­ted by the Free State of Bavaria. 

Our research focuses on (auto-)immune dis­eases, degen­er­at­ive dis­eases of the brain (Alzheimer’s) and the heart. We use human induced pluri­po­tent stem cell (iPSC) tech­no­lo­gies to develop dis­ease mod­els for the dis­cov­ery of novel drugs and cell ther­apies. In doing so, we enter into stra­tegic part­ner­ships with research insti­tu­tions and indus­trial companies.

We are look­ing for a sci­ent­ist to join our team (full-time pos­i­tion). Suit­able can­did­ates will join a vibrant and grow­ing start-up com­pany that devel­ops the next gen­er­a­tion of dis­ease mod­els and cell ther­apies by edit­ing and dif­fer­en­ti­at­ing human induced pluri­po­tent stem cells (hiPSC) into rel­ev­ant cells of interest.

Respons­ib­il­it­ies

  • Con­tri­bu­tion to research and devel­op­ment of novel ther­apies for neuro-degen­er­at­ive diseases
  • Estab­lish and main­tain cell lines for pro­duc­tion of pro­teins under qual­ity-con­trolled con­di­tions, e. g. CHO and HEK-293 cells
  • Optim­ize expres­sion levels of tran­si­ently trans­fec­ted and stable cell lines
  • Design, optim­ise, purify and char­ac­ter­ize thera­peutic antibodies
  • Estab­lish and per­form ana­lyt­ical stud­ies and method val­id­a­tions (using ELISA, FACS and related methods)
  • Con­trib­ute to the gen­er­a­tion of mas­ter cell banks under GMP conditions
  • Crit­ic­ally ana­lyze and inter­pret data and define real­istic timelines for studies
  • Work closely with and com­mu­nic­ate res­ults to internal teams as well as to external partners

Qual­i­fic­a­tions

  • Ph.D. in Bio­chem­istry, Pro­tein Engin­eer­ing , Immun­o­logy or related field
  • Mam­malian cell cul­ture, trans­fec­tions and pro­tein puri­fic­a­tion and char­ac­ter­iz­a­tion is essential
  • Thor­ough under­stand­ing or exper­i­ence in instru­mental ana­lyt­ics, pro­tein bio­phys­ics or qual­ity man­age­ment stand­ards would be a plus
  • Struc­tured and inde­pend­ent way of work­ing as well as ana­lyt­ical skills
  • Good com­mand of Eng­lish as well as German

Our offer

We offer the spe­cial oppor­tun­ity to help shape the devel­op­ment of a new research com­pany in an inter­dis­cip­lin­ary team with pion­eer­ing spirit. You will be involved in excit­ing tasks and per­sonal devel­op­ment. The salary will depend on qual­i­fic­a­tions and pro­fes­sional exper­i­ence and is cal­cu­lated in accord­ance with the civil ser­vice salary scales (TVL). We also offer sup­port with com­pany pen­sion schemes, a wide range of sports activ­it­ies and JobRad leas­ing. The pos­i­tion is ini­tially for two years with the pos­sib­il­ity of a per­man­ent extension.

Con­tact

Please send your cover let­ter and com­plete applic­a­tion doc­u­ments with CV, references/ recom­mend­a­tion let­ter to recruitment@isarbioscience.de. Please indic­ate “Sci­ent­ist Bio­chem­istry” in the sub­ject line. For ques­tions con­cern­ing this pos­i­tion please con­tact Dr. Chris­ti­ane Schiegerl,

  • Dr. Chris­ti­ane Schiegerl
    Dr. Chris­ti­ane Schiegerl

    Please do not hes­it­ate to con­tact me if you have any questions.

    089-356475-413

Apply now

Please send us your applic­a­tion doc­u­ments with CV, ref­er­ences or let­ters of recom­mend­a­tion as a PDF file.

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